首页|亲水性银离子敷料与磺胺嘧啶银治疗深Ⅱ度烧伤创面效果比较

亲水性银离子敷料与磺胺嘧啶银治疗深Ⅱ度烧伤创面效果比较

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目的 了解亲水性银离子敷料与磺胺嘧啶银治疗深Ⅱ度烧伤创面的效果.方法 深Ⅱ度烧伤病人100例,随机分为对照组和观察组,各50例.对照组应用磺胺嘧啶银治疗,观察组应用亲水性银离子敷料治疗,比较两组治疗后肿瘤坏死因子-α(TNF-α)、白细胞介素-6(IL-6)、视觉模拟评分(VAS)、不同时间点创面愈合率、创面愈合时间、不良反应发生率.结果 治疗后观察组TNF-α、IL-6低于对照组,差异有显著性(t=4.417、3.638,P<0.05);观察组VAS评分低于对照组,差异有显著性(t=11.369,P<0.05);观察组治疗第7、12、17天创面愈合率高于对照组,创面愈合时间短于对照组,差异有显著性(t=4.033~9.898,P<0.05).两组均无不良反应发生.结论 深Ⅱ度烧伤创面采用亲水性银离子敷料治疗效果优于磺胺嘧啶银,值得推广.
EFFECT OF HYDROPHILIC SILVER ION DRESSINGS VERSUS SILVER SULFADIAZINE IN TREATMENT OF DEEP SECOND-DEGREE BURN WOUNDS
Objective To investigate the effect of hydrophilic silver ion dressings versus silver sulfadiazine in the treatment of deep second-degree burn wounds.Methods A total of 100 patients with deep second-degree burns who received treatment in our hospital from February 2014 to February 2016 were equally and randomly divided into control group and observation group.The control group was treated with sliver sulfadiazine,while the observation group was treated with hydrophilic silver ion dressing.The two groups were compared in terms of the levels of tumor necrosis factor-α (TNF-α) and interleukin-6 (IL-6),Visual Analogue Scale (VAS) score,wound healing rate at different time points,wound healing time,and the incidence of adverse events after treatment.Results After treatment,the observation group had significantly lower levels of TNF-α and IL-6 and VAS score than the control group (t =3.638-11.369,P<0.05).The observation group had significantly higher wound healing rates on days 7,12,and 17 of treatment and significantly shorter wound healing time than the control group (t=4.033-9.898,P<0.05).No adverse events were seen in both groups.Conclusion Hydrophilic silver ion dressing has a better effect than silver sulfadiazine in the treatment of deep second degree burn wounds,so it holds promise for clinical application.

burnsocclusive dressingssilver sulfadiazinetreatment outcome

刘薇、彭金霞、蔡希雯

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十堰市太和医院(湖北医药学院附属医院)整形烧伤美容科,湖北十堰442000

烧伤 封闭敷料 磺胺嘧啶银 治疗结果

2017

齐鲁医学杂志
青岛大学医学院

齐鲁医学杂志

影响因子:0.609
ISSN:1008-0341
年,卷(期):2017.32(4)
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