首页|三阴性乳癌病人血清矿物质及脂质水平的检测

三阴性乳癌病人血清矿物质及脂质水平的检测

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目的 分析三阴性乳癌(TNBC)病人体内矿物质及各类脂质含量的特点.方法 检测并比较153例TNBC病人、152例Luminal A型乳癌病人及150例健康查体者体质量指数(BMI)以及血清钙(Ca)、磷(P)、镁(Mg)、三酰甘油(TG)、总胆固醇(TC)、高密度脂蛋白(HDL-C)、低密度脂蛋白(LDL-C)指标等含量.结果 TNBC病人BMI与其他两组比较差异无显著性(P>0.05).TNBC病人血清Ca、P、Mg、TG、LDL-C水平显著高于其他两组,差异有统计学意义(F=2.34~8.47,P<0.05);TNBC和Luminal A型乳癌病人HDL-C水平显著低于健康者,差异有统计学意义(F=8.465,P<0.05).结论 TNBC病人的矿物质及TG水平显著高于Luminal A型乳癌病人及健康者,HDL-C水平显著低于健康者.
SERUM THE RESEARCH OF THE LEVELS OF MINERALS AND THE VARIOUS LIPIDS METABOLISM IN PATIENTS WITH TRIPLE-NEGATIVE BREAST CANCER
Objective To analyze the levels of minerals and the various lipids metabolism in patients with triple-negative breast cancer (TNBC),and compare the differences of them in TNBC,Luminal A breast cancer and healthy population.Methods A total of 153 TNBC patients (TNBC group),152 patients with Luminal A breast cancer (LABC) (LABC group),and 150 healthy subjects (control group) were enrolled in this study.The following indices were measured and compared between the three groups:collect the data of body mass index (BMI),and levels of calcium (Ca),phosphorus (P),magnesium (Mg),triglyceride fat (TG),total cholesterol (TC),high-density lipoprotein (HDL-C),and low-density lipoprotein (LDL-C) in the bloodlevels from 153 TNBC patients,152 Luminal A breast cancer patients and 150 healthy people,and explore the differences among the three groups.Results There was no significant difference in BMI between the TNBC group and the other two groups (P>0.05).The TNBC group had significantly higher levels of Ca,P,Mg,TG,and LDL-C levels of the TNBC patients are significantly higher than the other two groups (F=2.34 8.47,P<0.05).And the control group had a significantly higher HDL-C levels of TNBC patients and Luminal A breast cancer patients are significantly lower than healthy peoplethe other two groups (F=8.465,P<0.05).These differences are all statistically significant.Conclusion TNBC patients have significantly higher the levels of minerals and TG level of TNBC patients are significantly higher than other two groups LABC patients and healthy subjects,and a significantly lowerthe HDL-C level of TNBC patients is lower than the healthy groupsubjects.

breast neoplasmslipid metabolismminerals

孙宁宁、明洁、丁燕美、梁惠

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青岛大学公共卫生学院,山东青岛266021

青岛大学附属医院乳腺病诊疗中心

乳房肿瘤 脂类代谢 矿物质

2017

齐鲁医学杂志
青岛大学医学院

齐鲁医学杂志

影响因子:0.609
ISSN:1008-0341
年,卷(期):2017.32(4)
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