首页|腮腺嗜酸细胞型黏液表皮样癌1例临床病理观察并文献复习

腮腺嗜酸细胞型黏液表皮样癌1例临床病理观察并文献复习

扫码查看
目的 探讨腮腺嗜酸细胞型黏液表皮样癌(OMEC)的临床病理学特点、诊断及鉴别诊断,提高对OMEC的认识.方法 总结1例腮腺OMEC的组织病理学及免疫组织化学特点,并复习相关文献.结果 光镜下观察,肿瘤细胞主要由嗜酸性细胞及少许含黏液细胞构成,肿瘤排列成腺样、筛状及实性巢状结构.免疫表型:肿瘤细胞CK、CK7、CK14、EMA、p63及MUC5AC均呈阳性,而CK20、S-100、SMA及Vimentin均呈阴性.结论 OMEC非常罕见,结合临床病理学特点及免疫组化染色有助于其诊断和鉴别诊断.
ONCOCYTIC MUCOEPIDERMOID CARCINOMA OF THE PAROTID GLAND: CLINICOPATHOLOGICAL STUDY OF A CASE AND LITERATURE REVIEW
Objective To investigate the clinicopathological features,diagnosis,and differential diagnosis of oncocytic mucoepidermoid carcinoma (OMEC) of the parotid gland,and to raise the awareness of this disease.Methods The histopathological features and immunohistochemical features of one patient with OMEC of the parotid gland were summarized and related literature was reviewed.Results Microscopic observation showed that tumor cells mainly consisted of eosinophils and mucous cells and were arranged in an adenoid,cribriform,or nest-like shape.As for immunophenotype,tumor cells had positive CK,CK7,CK14,EMA,p63,and MUC5AC and negative CK20,S-100,SMA,and Vimentin.Conclusion OMEC is an extremely rare type of mucoepidermoid carcinoma,and a combination of clinicopathological features and immunohistochemical staining may help with its diagnosis and differential diagnosis.

carcinoma, mucoepidermoideosinophilsparotid glandsalivary glands

张萌萌、姜维娜、贾冬梅、刘红云、陈桦、阎潇

展开 >

青岛市市立医院病理科,山东青岛 266071

青岛市市立医院口腔科,山东青岛 266071

癌,黏液表皮样 嗜酸细胞 腮腺 涎腺

2017

齐鲁医学杂志
青岛大学医学院

齐鲁医学杂志

影响因子:0.609
ISSN:1008-0341
年,卷(期):2017.32(4)
  • 3