CLINICAL EFFECT OF RETROPERITONEAL LAPAROSCOPIC PARTIAL NEPHRECTOMY WITH SELECTIVE RENAL ARTERY BRANCH CLAMPING IN TREATMENT OF RENAL TUMOR WITH A RENAL SCORE OF ≥7
Objective To investigate the clinical effect of retroperitoneal laparoscopic partial nephrectomy with selective renal artery branch clamping in the treatment of renal tumor patients with a RENAL score of ≥7.Methods A total of 63 renal tumor patients with a RENAL score of ≥7 who were hospitalized in The Affiliated Hospital of Qingdao University and Jiaozhou Central Hospital from June 2013 to December 2015 were enrolled and treated with selective renal artery branch clamping or standard partial nephrectomy.The two groups were compared in terms of time of operation,warm ischemia time,rate of positive resection margin,blood transfusion rate,intraoperative blood loss,postoperative complications,and length of hospital stay,as well as renal function at different time points.Results The standard partial nephrectomy group had a significantly shorter time of operation than the selective renal artery branch clamping group (t =4.859,P<0.05).There were no significant differences between the two groups in warm ischemia time,rate of positive resection margin,blood transfusion rate,intraoperative blood loss,incidence rates of postoperative complications,and length of hospital stay (P>0.05).At one month after surgery,the selective renal artery branch clamping group had a significantly greater reduction in estimated glomerular filtration rate (eGFR) compared with the standard partial nephrectomy group (t =2.687,P <0.05);at 12 months after surgery,there was no significant difference in eGFR between the two groups (P>0.05).Conclusion In renal tumor patients with a RENAL score of ≥7,retroperitoneal laparoscopic partial nephrectomy with selective renal artery branch clamping can protect their renal function in the early stage after surgery and does not increase intraoperative blood loss and postoperative complications.It is a safe and effective surgical method and thus holds promise for clinical application.