LOW-DOSE MULTISLICE SPIRAL CT COMBINED WITH CONTRAST-ENHANCED ULTRASOUND IN DIAGNOSIS OF SMALL HEPATOCELLULAR CARCINOMA
Objective To examine the clinical value of low-dose multislice spiral CT (MSCT) combined with contrast-enhanced ultrasound (CEUS) in the diagnosis of small hepatocellular carcinoma (SHCC).Methods CEUS and low-dose 64-slice spiral CT were performed on 79 patients who had liver space-occupying lesions on two-dimensional ultrasound.Postoperative pathology and biopsy results were used as the gold standards to determine the clinical value of CEUS and low-dose 64-slice spiral CT in the diagnosis of SHCC.Results A total of 89 lesions were identified in the 79 patients,and 89 lesions each were detected by CEUS and low-dose MSCT.There was no significant difference in the contrast enhancement features in the arterial phase between CEUS and MSCT (P＞0.05).Moreover,no significant difference was found between CEUS and MSCT in the detection of lesion profiles during the portal phase and delayed phase (P＞0.05).MSCT correctly diagnosed 37 malignant lesions,and had 78.72％ sensitivity and 85.71％ specificity for the diagnosis of SHCC.CEUS correctly diagnosed 39 malignant lesions,and had 82.98％ sen sitivity and 80.95％ specificity for the diagnosis of SHCC.CEUS combined with MSCT correctly diagnosed 43 malignant lesions,and had 91.49％ sensitivity,92.86％ specificity,8.51％ missed diagnosis rate,and 7.14％ misdiagnosis rate for the diagnosis of SHCC.Conclusion Low-dose MSCT combined with CEUS can effectively improve the accuracy of SHCC diagnosis.
NETL
NSTL
万方数据
维普
