POSITIVE ALARM RATE, DISTRIBUTION, AND DRUG RESISTANCE OF PATHOGENS IN 515 BLOOD CULTURE SAMPLES IN A HOSPITAL
Objective To investigate the positive alarm rate,distribution,and drug resistance of pathogenic bacteria isolated from blood culture samples.Methods The pathogens detected from 515 blood culture samples in our hospital from January 1 to December 31,2015 were analyzed retrospectively.Results The positive alarm rates of 515 blood culture samples in 12,24,48,and 72 h were 39.22％,71.26％,89.51％,and 95.73％,respectively.The top three bacteria were Escherichia coli (119 strains,23.11％),Klebsiella pneumonia (52 strains,10.10％),and Staphylococcus aureus (39 strains,7.57％).The common Enterobacteriaceae bacteria had a relatively high resistance to piperacillin,which was over 70.0％;however,they had high sensitivity to imipenem and meropenem.The resistance rate of Acinetobacter baumannii to commonly used antibacterials was over 75.0％,except for imipenem,meropenem,and piperacillin/tazobactam.The resistance rate of Pseudomonas aeruginosa was 42.9％ to ciprofloxacin and levofloxacin,and was 61.9 ％ to carbapenems.Among gram-positive cocci,all staphylococci had high resistance to penicillin,and had low resistance to vancomycin and linezolid.Conclusion Enterobacteriaceae bacteria are the main pathogenic bacteria isolated from blood cultures.Different bacteria show various resistance rates to commonly used antibacterials,with serious drug resistance.Timely monitoring of the changes in the distribution and drug resistance of pathogens from blood cultures provides a reference for rational and standardized application of antibacterials.
NETL
NSTL
万方数据
维普
