EFFECT OF CAROTID ARTERY STENTING ON COGNITIVE FUNCTION IN PATIENTS WITH CAROTID ARTERY STENOSIS
Objective To explore the effect of carotid artery stenting (CAS) on cognitive function in patients with carotid artery stenosis.Methods Totally 120 patients with carotid artery stenosis were enrolled in this study,including 60 patients who underwent CAS and 60 who received drug treatment.The cognitive function of patients in two groups was measured with Wechsler Adult Intelligence Scale-Revised in China (WAIS-RC) before treatment and at 3 days and 6 months after treatment.Results In the CAS group,the scores of knowledge,arithmetic,digit span,digit symbol,and comprehension at 3 days after treatment were significantly lower than those before treatment;the scores of digit symbol and digit span at 6 months after treatment were significantly higher than those before treatment or at 3 days after treatment (F=2.66-3.86,P<0.05).The score of block pattern in the drug treatment group at 3 days after treatment was significantly higher than that before treatment (F=3.80,P<0.05).Conclusion Compared with drug treatment,the carotid artery stenosis patients treated by CAS experience temporary cognitive decline in the early stage,but the long-term memory and attention will be improved.
carotid stenosisstentsangioplastycognitionrepeated measures analysis of variance