珠海市住院鼻咽癌患者626例临床首发症状调查分析
Clinical initial presentation research and analysis of 626 hospitalized patients with nasopharyngeal carcinoma in Zhuhai City
徐建慧 1陈新野 2王思阳 3梁子彬 3廖伟 2洪海裕2
作者信息
- 1. 中山市人民医院耳鼻咽喉头颈外科,广东中山528403
- 2. 中山大学附属第五医院耳鼻咽喉科,广东珠海519000
- 3. 中山大学附属第五医院放疗科,广东珠海519000
- 折叠
摘要
目的:通过对鼻咽癌首次住院接受治疗患者的患病情况调查,了解鼻咽癌在珠海地区的临床患病特点,并与既往资料比较,为早期诊断提供依据.方法:回顾性调查分析2003-03-2011-03中山大学附属第五医院首次住院的626例鼻咽癌患者的病例资料.按预先设计的调查表,收集患者的首发症状、淋巴结肿大转移及颅神经侵犯等情况,并进行统计分析.结果:患者首发症状主要为颈部包块、涕血、耳鸣等症状,其中颈部包块为最典型的首发症状,占27.8％,涕血占23.0％,耳鸣占17.7％.颈部淋巴结转移423例(67.6％)；在淋巴结转移的患者中,单侧转移314例(74.2％),双侧转移109例(25.8％),颈淋巴结以Ⅱ区转移最多见(90.0％),跳跃性转移率为4.7％.发生颅神经侵犯共103例(16.4％),以第V、Ⅵ和Ⅻ对颅神经受累率较高,分别占5.4％、5.1％和3.7％.结论:颈部包块是鼻咽癌的典型首发症状,临床确诊时多在Ⅲ期；在珠海对当地基本人群进行健康宣教及体检普查,对于早期发现鼻咽癌有着十分重要的意义.
Abstract
OBJECTIVE: According to clinical data of patients with nasopharyngeal carcinoma,to analyse clinical features of Zhuhai City,and compared with previous data to provide a preference for prevention and treatment of nasopharyngeal carcinoma. METHODS: Clinical data of 626 patients who were diagnosed as nasopharyngeal carcinoma in fifth affiliated hospital of Sun Yat-sen university from March 2003 to March 2011 was collected and symptoms,node distribution and cranial never paralysis were analyzed in this study according to designed table. RESULTS: The most common initial symptom was neck mass with an incidence of 27. 8% ,followed by nasal bleeding(23. 0%) and otological symptoms(17. 7%). Of 626 patients 423(67. 6%) had cervical lymphadenopathy at presentation. Of the 423 neck positive cases.the node involvement was unilateral in 74. 2% patients and bilateral in 25. 8%. The level Ⅱ was the most frequently involved area(90. 0%), with the incidence of skip metastases was 4. 7%. The cranial never involvement was 16. 4% and the involvement for cranial neverⅤ,Ⅵ and Ⅻ was 5. 4% ,5. 1% and 3. 7% respectively. CONCLUSIONS: Nasal symptoms is the most common initial manifestation,and clinical diognosis is most in stage Ⅲ. It is significant for early diagnosis to carry out medical examination for healthy population in Zhuhai.
关键词
鼻咽肿瘤/患病率/体征和症状,呼吸系统/早期诊断Key words
nasopharyngeal neoplasms/prevalence/signs and symptoms/respiratory/early diagnosis引用本文复制引用
出版年
2012
NETL
NSTL
维普
万方数据