Global burden of cervical cancer from 1990 to 2019
Objective To identify those countries making progress and those countries and regions requiring additional ef-forts to globally eliminate cervical cancer,by analyzing the temporal patterns of cervical cancer burden on a global,re-gional,and national scale over the past three decades.This will provide reference for achieving the global goal of elimina-ting cervical cancer proposed by the World Health Organization(WHO).Methods A linear regression model was used to analyze the temporal trends of cervical cancer incidence,death,and disability adjusted life years(DALYs)in the global disease burden 2019 database from 1990 to 2019 at global,regional,and national levels.Results Globally,between 1990 and 2019,cervical cancer incident cases increased from 335 642 in 1990 to 565 541 in 2019,with an annualized rate of change of 2.3％,and deaths increased from 184 527 to 280 479,with an annualized rate of change of 1.7％.The age-standardised incidence,mortality,and DALY rates decreased from 1990 to 2019 at the global level,as well as for all re-gions except Western Pacific Region,with annualized rates of change ranging from-1.2％to-0.1％.The increasing trends on age-standardised incidence and mortality rate were seen in 43 and 20 of 204 countries,respectively,and these countries were mainly in African region,especially Sub-Saharan region.Conclusion The increases in the absolute burden of cervical cancer worldwide,as well as the increase in incidence and mortality rates in certain African countries,highlighted the ur-gent need to develop and implement the policies to increase human papillomavirus vaccination coverage,screening coverage,and treatment rate,so as to achieve the ambitious goal of eliminating cervical cancer globally in near future.
cervical cancerincidencedeathsdisability-adjusted life years(DALY)time trends analysis
NETL
NSTL
万方数据
