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多参数MRI预测直肠癌淋巴结转移的研究进展

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目的 探讨多参数MRI(mpMRI)预测直肠癌淋巴结转移的研究进展、局限性以及未来发展趋势.方法 应用中国知网和PubMed数据库,以"磁共振、多参数成像、直肠癌、淋巴结转移"为中文关键词,"MRI、multiparametric imaging、rectal cancer、lymph node metastasis"为英文关键词,系统检索2017-01-01-2023-06-07相关文献.纳入标准:(1)直肠癌淋巴结转移的相关研究;(2)mpMRI对淋巴结转移诊断的相关研究.排除标准:(1)会议性、评论类等文献;(2)内容相似或重复的文献.最终纳入61篇文献进行分析.结果 与传统的计算机辅助诊断相比,mpMRI(对比增强MRI、弥散加权成像/表观扩散系数、T2加权图像等)能为医生提供更多的视角观察病变;与单一的CT图像相比,基于mpMRI的影像组学特征模型结合临床危险因素对直肠癌淋巴结转移具有更好的预测性能.结论mpMRI在预测直肠癌淋巴结转移方面具有较大的潜能,结合基于mpMRI的影像组学特征和深度学习的预测模型是其未来研究发展的方向之一.此外,有待开发更多的mpMRI以提高直肠癌患者术前淋巴结状态的预测,辅助医师做出最佳诊断,使患者的个体化治疗成为可能.
Research progress of multi-parameter MRI in predicting lymph node metastasis of rectal cancer
Objective We provided an overview of the research progress,limitations and future development trends of multi-parameter MRI(mpMRI)in predicting lymph nodes of rectal cancer.Methods Using the China National Knowl-edge Infrastructure(CNKI)database and PubMed retrieval system,relevant literature from 2017-01-01 to 2023-06-07 were retrieved with"MRI,multiparametric imaging,rectal cancer,lymph node metastasis"as keywords.Inclusion crite-ria:(1)Research related to lymph node metastasis in rectal cancer;(2)Research related to mpMRI imaging in lymph node metastasis.Exclusion criteria:(1)Conference literature,commentary literature,etc;(2)Literature with similar or repetitive content.Finally,61 articles were included for analysis.Results Compared to traditional computer-aided diag-nosis,mpMRI(contrast-enhanced MRI,diffusion weighted imaging/apparent diffusion coefficient,T2 weighted image)can provide doctors with more perspectives to observe lesions.Compared with a single CT image,the radiomics feature model based on mpMRI combined with clinical risk factors has better predictive performance for lymph node metastasis in rectal cancer.Conclusions mpMRI has great potential in predicting lymph node metastasis in rectal cancer.Combining radiomics features based on mpMRI and deep learning prediction model is one of its future research directions.In addi-tion,more mpMRI need to be developed to improve the prediction of preoperative lymph node status in rectal cancer pa-tients,assist physicians in making the best diagnosis,and make personalized treatment possible for patients.

MRImultiparametric imaging imagingrectal cancerlymph node metastasisreview literature

邹静敏、王华东、马长升、王世江、马燕

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山东第一医科大学(山东省医学科学院)研究生部,山东济南 250117

山东省肿瘤防治研究院(山东省肿瘤医院)消化内科二病区,山东第一医科大学(山东省医学科学院),山东济南 250117

磁共振 多参数成像 直肠癌 淋巴结转移 综述文献

山东省医学会临床科研基金山东省医学会临床科研基金山东省医务职工科技创新计划山东省中医药科技项目

YXH2022ZX02197YXH2022ZX02025SDYWZGKCJH2022008M-2022225

2024

中华肿瘤防治杂志
中华预防医学会 山东省肿瘤防治研究院

中华肿瘤防治杂志

CSTPCD北大核心
影响因子:1.292
ISSN:1673-5269
年,卷(期):2024.31(4)
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