Epidemiological characteristics of leukemia in Wuwei City,Gansu Province in 2018 and trends from 2010 to 2018
Objective To analyze the characteristics of leukemia incidence and death in Wuwei City,Gansu Province in 2018 and trends of leukemia incidence and death from 2010 to 2018.Methods The incidence,death and population data of leu-kemia reported by tumor registration project sites in Wuwei City from 2010 to 2018,which met the data quality standards were collected and analyzed.The crude incidence/mortality rates,standardized incidence/mortality rates,cumulative inci-dence/mortality rates were calculated by gender and age group.The annual percentage change(APC)of the age-standard-ized incidence/mortality rates of leukemia in Wuwei City from 2010 to 2018 was analyzed by Joinpoint 5.0 linear regres-sion model,and the incidence and mortality trends of leukemia were analyzed.The Chinese population standardized rate(CPSR)and the world standardized rate(WPSR)were calculated using the age distribution of the 2000 national census and Segi world standard population age composition respectively.Results In 2018,the incidence rate of leukemia in Wu-wei City was 4.70/100 000,the standardized incidence rate was 3.81/100 000,the mortality rate was 1.74/100 000,and the standardized mortality rate was 1.52/100 000.The standardized incidence and mortality rates of leukemia in males were both higher than those in females(4.85/100 000 vs 2.73/100 000;1.75/100 000 vs 1.30/100 000);The incidence of leukemia mainly concentrated in the age group of 50 to 84 years old,peaking in the age group of 75 to 79 years old,and the death population mainly concentrated in the age group of 15 to 19 years old,40 to 59 years old and 65 to 79 years old.Among different types of leukemias,myeloid leukemia had a higher standardized incidence rate than lymphoid leukemia(2.69/100 000 vs 0.58/100 000)and a lower mortality than lymphoid leukemia(0.21/100 000 vs 0.37/100 000).From 2010 to 2015,the standardized incidence of leukemia in Wuwei City showed an increasing trend(APC of 19.91％,95％CI:1.61％-41.47％),which was statistically significant(t=3.05,P=0.038),while from 2015 to 2018,the APC was-8.45％,with no statistical significance(t=-0.72,P=0.513).From 2010 to 2018,the standardized mortality rate of leukemia in Wuwei City showed an increasing trend(APC of 9.04％,95％CI:2.01％-16.58％),and the differ-ence was statistically significant(t=3.06,P=0.018).Conclusions In 2018,the incidence and mortality of leukemia in Wuwei City were at relatively low levels,but from 2010 to 2018,the incidence and death of leukemia in Wuwei City showed an increasing trend,and the prevention and control situation was still severe.Relevant departments should pay at-tention to the prevention and treatment of leukemia,strengthen the primary prevention of leukemia health education for key groups,take targeted intervention measures,and enhance the health awareness of residents.
leukemiaincidence ratemortalityannual percentage change(APC)Wuwei City
NETL
NSTL
万方数据
