Results of screening and follow-up of early detection and treatment project for upper gastrointestinal cancer in Huaihe River basin of Tengzhou City from 2010 to 2022
Objective To analyze the results of screening and follow-up of the early detection and treatment project for up-per gastrointestinal cancer in Huaihe River basin of Tengzhou City from 2010 to 2022,and to grasp the changing trends of screening results.Methods Based on the cancer screening program conducted in Tengzhou City from 2010 to 2022,the databases of screening and follow-up were analyzed,while the detection rates,the early stage diagnosis rates and treatment rates were calculated respectively.The x2 test was used to analyze the differences between the high-risk rate,detection rate,early stage diagnosis rate and treatment rate among different groups,and the trend x2 test was used to ana-lyze the trend changes of high-risk rate,detection rate,early stage diagnosis rate and treatment rate in different years.Re-sults A total of 73 282 residents participated in upper gastrointestinal cancer risk assessment questionnaire from 2010 to 2022,and the high-risk rate was 45.85%(33 598/73 282);23 478 person-times of endoscopic screening and follow-up re-view included 22 925 person-times of initial screening and 553 person-times of follow-up review.Among the subjects in preliminary screening,the detection rate,early stage diagnosis rate and treatment rate were 0.64%(147/22 925),76.87%(113/147)and 74.15%(109/147),respectively.There was no statistically significant difference in the detection rate,early diagnosis rate,and treatment rate of upper gastrointestinal cancer among the initial screening population over the 13-year period(the trend x2 test:the detection rate x2=2.62,P=0.106;the early stage diagnosis rate x2=2.31,P=0.129;the treatment rate x2=1.07,P=0.302).Among the subjects in follow-up,the detection rate,early stage diagno-sis rate and treatment rate were 4.52%(25/553),80.00%(20/25)and 60.00%(15/25),respectively.There was signifi-cant difference in the detection rate of upper gastrointestinal cancer among preliminary screening and follow-up(x2=111.75,P<0.001).Conclusions The risk rate of upper gastrointestinal cancer was higher in Tengzhou City of Huaihe River basin from 2010 to 2022,but the detection rate of upper gastrointestinal cancer in Cancer Screening Program was lower.We should take cancer screening as the focus of chronic disease prevention and control,further improve the stand-ardized and long-term screening mechanism,strengthen publicity and education of cancer prevention knowledge,thus to improve the screening effectiveness.
upper gastrointestinal cancerscreeningHuaihe River basinfollow-up