Macrophages are part of the innate immune system and the mononuclear phagocyte system,widely present in tissue structures including the heart.Myocardial infarction is a severe ischemic disease,and research indicates that myocardial macrophages play a significant role in post-infarction cardiac metabolism and contribute to the benefits associated with cellular therapy post-myocardial infarction.Thus,optimizing the metabolism of myocardial macrophages could potentially achieve the best cardiac protection.
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