Investigation on the endemic status and risk factors of hemorrhagic fever with renal syndrome in Gansu Province from 2017 to 2022
Objective To analyze the epidemiological patterns of hemorrhagic fever with renal syndrome(HFRS)in Gansu Province,and investigate the primary risk factors affecting the incidence of HFRS among residents for reference in formulating targeted strategies and measures for prevention and control of this infection.Methods The relevant in-formation of HFRS cases reported in Gansu Province from 2017 to 2022 was collected through the China Disease Pre-vention and Control Information System,and descriptive analysis was conducted on the temporal,regional and demo-graphic distribution of HFRS cases.Furthermore,a case-control study was carried out on HFRS cases reported in Min County,Dingxi City from 2020 to 2022 to analyze the primary risk factors affecting the incidence of this acute zoonotic condition.Results In total,747 cases of HFRS were reported in Gansu Province from 2017 to 2022,with an average annual incidence of 0.50 per 100 000 population.The highest incidence occurred in 2019,reaching 1.28 per 100 000 population.The reported cases were 469(62.78%)for males,and 278(37.22%)for females,with an average annual re-ported incidence of 0.61/100 000 and 0.38/100 000 population,respectively for each gender.In different age groups,the number of reported cases was the largest in population aged 45-59 years(296 cases,39.63%),followed by those aged 30-44 years(184 cases,24.63%).Farmers were the most involved in HFRS(487 cases,65.19%),followed by herdsmen(133 cases,17.81%).The incidence of HFRS was mainly concentrated in October to December(569 cases,76.17%),with the peak occurring in November(262 cases,35.07%).The reported cases were mainly in Xiahe County,Min Coun-ty and Lingtai County,with a cumulative number of reported cases being 571(76.44%).The results of the case-control study showed that the potential risks for HFRS were associated with absence of vaccination against HFRS(OR=5.99),presence of rat cavity in the house(OR=3.99),no wearing a mask when digging and organizing herbs(OR=10.45),in-take of food contaminated by rodents(OR=5.49),contact with rodents or rodent feces(OR=11.64),and drinking un-boiled water(OR=6.97).Conclusion From 2017 to 2022,the incidence of HFRS in Gansu Province showed a trend of first increasing and then decreasing,with a concentrated period and area of high incidence.For the areas of high inci-dence,preventive vaccination,health education and improvement of the living environment should be carried out in due course to strengthen residents'awareness of protection and guide them to develop better dietary and hygienic habits,so as to reduce the risk of the infection.
Hemorrhagic fever with renal syndromeEpidemiological characteristicsRisk factorsCase-control studiesGansu Province
NETL
NSTL
万方数据
