Study on the Secondary Metabolites of Marine Streptomyces Sporoverrucosus 33510
The secondary metabolites of marine actinomycete Streptomyces sporoverrucosus 33510 were studied in order to obtain bioactive compounds.The compounds were separated and purified by column chromatography,semi-preparative liquid chromatography and other chromatographic methods.Ten compounds were identified as cyclo(D-Pro-D-Leu)(1),bisphenol A(2),methylp-hydroxyphenylacetate(3),N-phenethylacetamide(4),3-indole-methylethanoate(5),dibutyl phthalate(6),cyclo(D-Pro-L-Leu)(7),cyclo(D-Pro-L-Ile)(8),cyclo(L-Pro-L-Phe)(9),and cyclo(L-Leu-L-Val)(10).Eight compounds were isolated from Streptomyces sporoverrucosus for the first time.Compound 2 showed inhibitory activity against Cryphonectria parasitica.
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