The secondary metabolites of marine actinomycete Streptomyces sporoverrucosus 33510 were studied in order to obtain bioactive compounds.The compounds were separated and purified by column chromatography,semi-preparative liquid chromatography and other chromatographic methods.Ten compounds were identified as cyclo(D-Pro-D-Leu)(1),bisphenol A(2),methylp-hydroxyphenylacetate(3),N-phenethylacetamide(4),3-indole-methylethanoate(5),dibutyl phthalate(6),cyclo(D-Pro-L-Leu)(7),cyclo(D-Pro-L-Ile)(8),cyclo(L-Pro-L-Phe)(9),and cyclo(L-Leu-L-Val)(10).Eight compounds were isolated from Streptomyces sporoverrucosus for the first time.Compound 2 showed inhibitory activity against Cryphonectria parasitica.
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