Surface Nano-Structural Modification of Gradient Porous Titanium Alloy Scaffolds by 3D Printing
Micrometer-grade porous titanium alloy scaffolds with gradient structure were prepared by 3D printing technology to meet the personalized needs of different patients for bone defect repair scaffolds.However,due to the biological inertia of titanium alloy itself,the bone integration ability of porous titanium alloy scaffolds is poor after implantation.In order to improve the biological activity of scaffolds,nanostructured modification of the porous scaffold surface was performed by electrochemical anodic oxidation.The influence of oxidation voltage,oxidation time and electrolyte on the preparation of TNTs on the surface of gradient porous titanium alloy was explored.The results show that when the two-step anodic oxidation method is used,and the composition of the electrolyte is glycol solution containing 0.3wt%ammonium fluoride+2vol%deionized water+1.5 mol/L lactic acid,and the oxidation voltage is 100 V,the oxidation time is 1h,TNTs coating with high ordered morphology can be prepared on the surface of the scaffold.After oxidation treatment,the porous titanium alloy scaffold is annealed at 500℃,the crystal structure of the surface TNTs changes from amorphous structure to the mixed crystal structure of anatase and rutile,which is more favorable for protein adsorption and cell proliferation.Through electrochemical corrosion test,it is found that the porous titanium alloy scaffold treated by anodic oxidation has better corrosion resistance.
3D printingporous titanium alloyanodic oxidationsurface modification
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