The composition of antibiotic contamination in the main rivers of the Jinjiang River Basin in Chengdu during the dry and abundant periods was analyzed with the solid-phase extraction-high performance liquid chromatography-tandem mass spectrometry,involving 26 antibiotics of 6 categories,and the ecological risk of 20 antibiotics in the Jinjiang River Basin was assessed by the risk entropy value method.The results showed that 25 antibiotics of 6 categories were detected in the Jinjiang River Basin,among which β-lactams had the highest concentration,ranging from 314 ng/L to 716 ng/L.The concentration of antibiotics in the river was influenced by the season,showing a trend that the pollution concentration was higher in the dry period than in the abundant period.Penicillin G,amoxicillin,cefotaxime,sulfamethoxazole,sarafloxacin and dehydrated erythromycin in the Jinjiang River Basin showed high risk,ampicillin,erythromycin,roxithromycin,ofloxacin and sulfadimethoxine showed medium risk,and the rest of antibiotics showed low risk.
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