创伤后应激障碍快感缺失症状的研究进展
Research advances in anhedonia symptoms of post-traumatic stress disorder
万嘉琛 1李根 2曹成琦 1王力1
作者信息
- 1. 中国科学院心理研究所心理健康重点实验室,北京 100101;中国科学院大学心理学系,北京 100049
- 2. 上海纽约大学全球健康公平研究中心,上海 200122
- 折叠
摘要
快感缺失是指愉悦感受的缺乏,约三分之二的创伤后应激障碍(PTSD)患者存在快感缺失症状.快感缺失症状是PTSD的独立症状维度,在创伤后心理病理过程中发挥着重要作用,且与创伤后应激反应的持续、更严重的功能受损和更差的治疗反应密切相关.本文就PTSD快感缺失症状的定义、心理病理机制、遗传学基础以及神经生物学基础进行探讨,为未来快感缺失症状的研究提供思路.
Abstract
Anhedonia is defined as the reduction of pleasure and reward-seeking behavior,and it is prevalent in approximately two-thirds of individuals diagnosed with post-traumatic stress disorder(PTSD).Numerous empirical studies have consistently demonstrated that anhedonia represents an independent symptom dimension of PTSD.Furthermore,additional investigations have revealed that anhedonia plays a crucial role in the psychopathology of PTSD,contributing to the maintenance of post-traumatic stress responses,as well as more severe functional impairment and reduced therapeutic responsiveness.This paper aims to discuss the definition,psychopathology,genetic mechanisms and neurobiological underpinnings of anhedonia in PTSD,thus providing insights for future research on anhedonic symptoms.
关键词
创伤后应激障碍/快感缺失/心理病理/神经影像/遗传Key words
Post-traumatic stress disorder/Anhedonia/Psychopathology/Nneuroimaging/Genetic mechanisms引用本文复制引用
基金项目
国家自然科学基金联合基金重点项目支持(U21A20364)
国家自然科学基金青年项目(32300918)
出版年
2024
国家科技期刊平台
NSTL
万方数据