摘要
背景 认知功能下降是精神分裂症患者的标志性症状,经颅直流电刺激(tDCS)可改善患者的认知功能.目的对tDCS改善精神分裂症患者认知功能的效果进行系统评价,为精神分裂症患者认知功能的临床干预提供参考.方法 于2023年9月12日,计算机检索中国知网、万方、维普、PubMed、CINAHL和PsycINFO数据库,系统收集有关tDCS改善精神分裂症患者认知功能的随机对照试验.采用Cochrane偏倚风险评估工具2.0版本(RoB 2.0)对纳入文献的偏倚风险进行评价.结果 共纳入17篇文献,包含953例精神分裂症患者.tDCS对精神分裂症患者的信息处理速度、注意力、工作记忆、执行功能、学习能力等认知功能均有改善作用.结论 tDCS可能对精神分裂症患者的认知功能具有改善作用.
Abstract
Background Decline in cognitive function is considered a hallmark of schizophrenia,and transcranial direct current stimulation(tDCS)has developed as a promising tool for cognitive enhancement.Objective To systematically evaluate the effect of tDCS on improving cognitive functioning in patients with schizophrenia,so as to provide references for clinical intervention of cognitive function in patients with schizophrenia.Methods A computer-based systematic search was conducted on September 12,2023 through CNKI,Wanfang,VIP,PubMed,CINAHL and PsycINFO databases,and randomized controlled trials relevant to the efficacy of tDCS for management of cognitive function in patients with schizophrenia were collected.The risk of bias was assessed using the Cochrane Risk of Bias Tool for Randomized Trials(RoB 2.0).Results A total of 17 articles were included,including 953 patients with schizophrenia.TDCS has an improvement effect on cognitive functions such as information processing speed,attention,working memory,executive function and learning ability in patients with schizophrenia.Conclusion tDCS may have an effect on improving cognitive deficits in patients with schizophrenia.
国家科技期刊平台
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万方数据