Study on the Preparation of Old Ginger Enzyme by Probiotic Materia Medica Fermentation Technology and Its Effect on Cold Coagulation Blood Stasis Model in Rats
In this paper,the effect of old ginger enzyme produced from ginger,brown sugar,jujube and isomaltooligosaccharide on alleviating the adverse reactions caused by cold coagulation and blood stasis was studied.By establishing the rat model of cold coagulation and blood stasis,the rats were divided into three groups:low dose group,middle dose group and high dose group.Observe the basic characteristics of rats,such as body weight,writhing reaction,determine the organ index of uterus,ovary and kidney,and the hemorheological characteristics before and after taking it,and analyze the numerical changes of PGF2α and PGE2,Ca2+overload and oxidative stress reaction.The results showed that compared with the model group,the low-dose group,middle-dose group and high-dose group improved the body weight and basic indexes of rats,and the writhing times and blood viscosity decreased significantly in the high-dose group,it shows that old ginger enzyme helps to alleviate the adverse reactions caused by cold coagulation and blood stasis and has no effect on health.The ratio of PGF2α to PGE2 in the high dose group was significantly lower than that in the model group,the overload of Ca2+was improved and the activity of SOD enzyme was increased.It shows that old ginger enzyme can improve the syndrome of cold coagulation and blood stasis to some extent.
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