Study on the Process Condition of Lovastatin Production by Monascus Solid-State Fermentation
In this paper,the solid-state fermentation conditions of lovastatin producing strain Monascus S-01 were studied,and the best solid-state fermentation conditions were determined:rice 2 500 g,glycerium 75 g,peptone 175 g,initial moisture content 40%,bottling with 350 g/1.5 L,inoculum volume 25%,30℃for 7 d(pre-fermentation),23℃for 33 d(post-fermentation),optimized yield of lovastatin by Monascus in solid-state fermentation was 14.38 mg/g,acid(ring-opening)lovastatin was 9.35 mg/g,and the proportion was 65.02%.This study has certain guiding significance for the industrial production of functional Monascus.
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