Advances in Research on the Antibacterial Mechanism of Chlorogenic Acid Against Foodborne Pathogens
Chlorogenic acid is a natural phenolic compound that can be effectively extracted from a variety of plants in nature,because it shows good inhibitory effect on a variety of foodborne pathogens both in vitro and in food matrices,it has a broad application prospect in the field of food safety.At present,it has been found that the antibacterial mechanism of chlorogenic acid mainly involves acting on bacterial cell walls and membranes to increase their permeability,affecting the ability of cell aggregation and the formation of biofilms,inducing intracellular ROS depletion,affecting enzyme activity to interfere with metabolism,and damaging DNA.This article summarizes the antibacterial effects and mechanisms of chlorogenic acid on foodborne pathogen in vitro and in vivo,aiming to provide important theoretical basis for in-depth research on the antibacterial mechanism of chlorogenic acid and the development of new eco-friendly antibacterial agents.
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