Interleukin 10(IL-10)is a multifunctional cytokine that participates in the immunity of the body.It is secreted by various immune cells such as monocytes and macrophages,and plays an important role in the develop-ment of various diseases such as tumor,infection and immune diseases.A variety of scleractinian fish IL-10 has been clonally expressed and has shown immunomodulatory effects,and there are a number of studies on the biolo-gical activity,mechanism of action,and regulatory mechanism of IL-10 in fish.To provide a reference for future studies and applications of fish IL-10,a literature review is conducted in terms of its genetic structure,transcrip-tional expression,origin and evolution,biological activities and functions,as well as fish IL-10 receptor and sig-naling pathway.
国家科技期刊平台
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