Objective To investigate the risk factors for the development of FI in preterm infants with NRDS in the NIP-PV and NCPAP models.Methods Clinical data of 246 preterm infants who were first applied with either NIPPV or NCPAP and diagnosed with NRDS were retrospectively analyzed and divided into NIPPV and NCPAP groups according to the modality,and ac-cording to whether FI occurred or not was divided into FI and FT groups to explore the risk factors for the occurrence of FI in pre-term infants.Results ①Among the 136 cases in the NIPPV group and 110 cases in the NCPAP group,the differences between the two groups in terms of occurrence of FI,abdominal distension,feeding status,and length of hospital stay were statistically sig-nificant(P＜0.05).②Among the 96 cases in the FI group and 150 cases in the FT group,the differences between them in terms of birth body mass,gestational age,twin births,the amount of milk opened for the first time after birth,and the mode of non-invasive ventilation were statistically significant(P＜0.05),and Logistics regression analysis found that the application of the NIPPV mode and twin births were the independent risk factors for FI,comparing with the NCPAP mode(P =0.010,OR =2.105;P =0.012,OR =2.151).③Among the NIPPV models,Logistic regression analysis found that PIP≥14 cmH2 O was an independ-ent risk factor for FI(P =0.001,OR =4.073),and maternal comorbid gestational diabetes was a protective factor(P =0.004,OR =0.292).Conclusion When NRDS occurs in preterm infants,the risk of FI is higher with the NIPPV model than with the NCPAP model.Excessive PIP and twin births are risk factors for the development of FI,which can prolong the duration of total en-teral feeding and hospitalisation,and need to be closely monitored by clinicians.
维普
万方数据