PFNA与InterTAN髓内钉联合抗骨质疏松治疗骨质疏松性粗隆间骨折的效果
Effect of PFNA and InterTAN Intramedullary Nail Combined with Anti-Osteoporosis Treatment of Osteoporotic Intertrochanteric Fracture
吴东发1
作者信息
- 1. 余干楚东医院,江西 上饶 335100
- 折叠
摘要
目的:探讨防旋股骨近端髓内钉(PFNA)与联合拉力交锁髓内钉系统(InterTAN)髓内钉联合抗骨质疏松治疗骨质疏松性粗隆间骨折的效果.方法:选取我院 2021年 7月—2022年 11月收治的 65例骨质疏松性粗隆间骨折患者作为研究对象,根据随机数字表法将其分为 2组.传统组(n=32)采用PFNA治疗,试验组(n=33)采用InterTAN治疗,比较 2组患者的各项临床指标、骨代谢指标、骨密度变化情况、髋关节功能的改善及并发症的发生情况.结果:试验组手术时间、住院天数、下地负重时间均短于传统组,手术切口长度短于传统组,术中出血量少于传统组,组间差异有统计学意义(P<0.05).治疗 3个月后,2组血清骨钙素(BGP)、血清骨碱性磷酸酶(BALP)表达及股骨大粗隆与股骨颈密度均较治疗前上升,且试验组高于传统组,抗酒石酸酸性磷酸酶 5b(TRACP-5b)表达均较治疗前降低,且试验组低于传统组,差异有统计学意义(P<0.05);2组Harris髋关节功能量表各个维度评分均较治疗前升高,且试验组高于传统组,差异有统计学意义(P<0.05).试验组不良反应发生率为 9.09%,低于传统组的 28.12%,差异有统计学意义(P<0.05).结论:通过运用PFNA术能够改善骨质疏松性粗隆间骨折患者骨代谢水平及骨密度修复,促进关节功能的恢复,缩短各项治疗时间,减少不良反应的发生.
Abstract
Objective:To investigate the effect of the combined anti-rotation proximal femoral intramedullary nail(PFNA)and combined tension locking intramedullary nail system(InterTAN)in the treatment of osteoporotic intertrochanteric fracture.Methods:65 patients with osteoporotic intertrochanteric fracture admitted to our hospital from July 2021 to November 2022 were selected as the study objects and divided into two groups according to random number table method.The traditional group(n=32)was treated with PFNA,and the experimental group(n=33)was treated with InterTAN.Clinical indexes,bone metabolism indexes,changes in bone density,improvement in hip function and occurrence of complications were compared between the two groups.Results:The operation time,hospitalization days and weight-bearing time of experimental groups were shorter than that of traditional group,the length of surgical incision was shorter,and the amount of intraoperative blood loss was less than that of traditional group,with statistical significance(P<0.05).After 3 months of treatment,the expression of serum osteocalcin(BGP),serum bone alkaline phosphatase(BALP)and the density of femoral greater trochosis and femoral neck in 2 groups were increased compared with before treatment,and the expression of tartrate-resistant acid phosphatase 5b(TRACP-5b)in experimental group was higher than that in traditional group,and the expression of tartrate-resistant acid phosphatase 5B in experimental group was lower than that in traditional group,the difference was statistically significant(P<0.05);the scores of all dimensions of Harris hip function scale in 2 groups were higher than before treatment,and the test group was higher than the traditional group,with statistical significance(P<0.05).The incidence of adverse reactions in experimental group was 9.09%,which was lower than 28.12%in traditional group,and the difference was statistically significant(P<0.05).Conclusion:The use of PFNA can improve bone metabolism and bone density repair in patients with osteoporotic intervertebral fractures,promote joint function recovery,shorten treatment time,and reduce the incidence of adverse reactions.
关键词
防旋股骨近端髓内钉/联合拉力交锁髓内钉系统/骨质疏松/骨质疏松性粗隆间骨折Key words
Antirotation femoral proximal intramedullary nail/Combined tension interlocking intramedullary nail system/Osteoporosis/Osteoporotic intertrochanteric fracture引用本文复制引用
出版年
2024
国家科技期刊平台
NSTL
万方数据