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手术与辅助治疗对膝关节骨性关节炎患者的临床疗效

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目的:探讨富血小板血浆联合三氧大自血疗法辅助关节镜治疗对膝关节骨性关节炎患者预后及关节功能的影响。方法:选取 2016 年 1 月-2022 年 1月我院收治的 80例膝关节骨性关节炎患者为研究对象,依据治疗方法的差异将其分为观察组与对照组,每组 40 例。对照组采用三氧大自血疗法辅助关节镜治疗,观察组采用富血小板血浆联合三氧大自血疗法辅助关节镜治疗,对比 2 组患者的血清炎症因子水平、膝关节Lysholm功能量表各维度评分、膝关节活动度、疼痛视觉模拟(VAS)评分和临床疗效。结果:治疗后,观察组血清炎症因子水平低于对照组,膝关节Lysholm功能量表评分的跛行、肿胀以及疼痛 3 个维度评分均高于对照组,膝关节活动度大于对照组,VAS评分低于对照组,组间差异有统计学意义(P<0。05);观察组治疗总有效率为100。00%,大于对照组的 85。00%,差异有统计学意义(P<0。05)。结论:对于膝关节骨性关节炎患者使用富血小板血浆联合三氧大自血疗法辅助关节镜治疗,能够显著降低患者关节液中炎症因子水平,较大程度缓解炎症反应,并可以极大减轻患者疼痛,提高患者膝关节功能,增大膝关节活动度,并且能够提高临床治疗效果。
Clinical Effect of Surgery and Adjuvant Therapy on Patients with Knee Osteoarthritis
Objective:To investigate the effect of platelet-rich plasma combined with trioxy autohemotherapy assisted arthroscopy on the prognosis and joint function of patients with knee osteoarthritis.Methods:80 patients with knee joint osteoarthritis treated in our hospital from January 2016 to January 2022 were selected as the study objects,and were divided into an observation group and a control group according to the differences in treatment methods,with 40 cases in each group.The control group was treated with trioxia auto-blood therapy assisted arthroscopy,and the observation group was treated with platele t-rich plasma combined with trioxia autoblood therapy assisted arthroscopy.Serum inflammatory factor levels,Lysholm score of knee function scale scores,knee motion,pain Visual Analogue Score and clinical efficacy of the two groups were compared.Results:After treatment,the levels of serum inflammatory factors in the observation group were lower than those in the control group,the scores of lameness,swelling and pain in Lysholm of knee joint were higher than those in the control group,the knee joint motion was higher than that in the control group,and the VAS score was low-er than that in the control group,with statistical significance(P<0.05).The total effective rate of observation group was 100.00%,which was higher than that of control group 85.00%,and the difference was statistically significant(P<0.05).Conclusion:For patients with knee osteoarthritis,the use of platelet-rich plasma combined with trioxy autoblood therapy as an adjuvant arthroscopic treatment can significantly reduce the level of inflammatory factors in the joint fluid of patients,alleviate the inflammatory response to a large extent,greatly reduce the pain of patients,improve the function of the knee joint,increase the mobility of the knee joint,and improve the clini-cal treatment effect.It is worth promoting in clinical practice.

Platelet-rich plasmaTrioxy self-blood therapyKnee osteoarthritisInfluence

朱春冀、王权、高滔、文伟、高颐、张正学、雷洲洋

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昭通市第一人民医院骨二科,云南 昭通 657000

富血小板血浆 三氧大自血疗法 膝关节骨性关节炎 影响

2024

中国伤残医学
中国康复医学会,黑龙江省截瘫研究所

中国伤残医学

影响因子:0.451
ISSN:1673-6567
年,卷(期):2024.32(6)