首页|经鼻高流量湿化吸氧与无创通气治疗病毒性肺炎致呼吸衰竭患者的效果分析

经鼻高流量湿化吸氧与无创通气治疗病毒性肺炎致呼吸衰竭患者的效果分析

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目的:探讨经鼻高流量湿化吸氧(NFNC)与无创通气(NIV)治疗病毒性肺炎致呼吸衰竭患者的临床效果。方法:回顾性选取 2021年 12月—2022年 12月吉安市中心人民医院收治的120例病毒性肺炎致呼吸衰竭患者资料为研究对象,根据发病后 6 h内呼吸支持方案的不同将患者分为NIV组与HFNC组,每组 60例。NIV组采用NIV治疗,HFNC组采用HFNC治疗。比较两组的住院时间、住院费用及舒适度评分、呼吸功能、气管插管率与并发症发生情况、心理状态。结果:HFNC组住院时间短于NIV组,住院费用低于NIV组,舒适度评分高于NIV组,差异均有统计学意义(P<0。05)。治疗前及治疗后 12、24、48 h,两组呼吸功能比较,差异均无统计学意义(P>0。05)。HFNC组并发症发生率为 10。00%,低于NIV组的 25。00%,差异有统计学意义(P<0。05);HFNC组气管插管率为 18。33%,低于NIV组的 23。33%,但差异无统计学意义(P>0。05)。治疗后 28 d,两组汉密尔顿焦虑量表、汉密尔顿抑郁量表评分均低于治疗前,且HFNC组均低于NIV组,差异均有统计学意义(P<0。05)。结论:病毒性肺炎致呼吸衰竭患者经HFNC与NIV治疗后的呼吸功能改善效果基本相当,但HFNC的舒适度相对更高,并发症发生率更低,患者心理状态更好,有利于住院时间的缩短与住院费用的降低,临床应用价值更高。
Effect Analysis of High Flow Nasal Cannula and Non-Invasive Ventilator in the Treatment of Respiratory Failure Caused by Viral Pneumonia
Objective:To investigate the clinical effect of high flow nasal cannula(HFNC)and non-invasive ventilator(NIV)in the treatment of respiratory failure caused by viral pneumonia.Methods:Data of 120 patients with respiratory failure caused by viral pneumonia admitted to Ji'an Central People's Hospital from December 2021 to December 2022 were retrospectively selected as the study objects.According to different respiratory support programs within 6 h after onset,the patients were divided into NIV group and a HFNC group,with 60 cases in each group.The NIV group was treated with NIV,the HFNC group was treated with HFNC.The length of stay,hospitalization cost and comfort score,respiratory function,tracheal intubation rate and complications,psychological state of the two groups were compared.Results:The hospital stay of the HFNC group was shorter than that of the NIV group,the hospital cost was lower than that of the NIV group,and the comfort score was higher than that of the NIV group,with statistical significance(P<0.05).There were no significant differences in respiratory function between the two groups before treatment and 12,24 and 48 h after treatment(P>0.05).The incidence of complications in the HFNC group was 10.00%,which was lower than 25.00%in the NIV group,with statistical significance(P<0.05).The tracheal intubation rate in the HFNC group was 18.33%,which was lower than 23.33%in the NIV group,but the difference was not statistically significant(P>0.05).Twenty eight days after treatment,the scores of Hamilton Anxiety Scale and Hamilton Depression Scale in both groups were lower than before treatment,and those in the HFNC group were lower than those in the NIV group,with statistical significance(P<0.05).Conclusion:The improvement of respiratory function in patients with respiratory failure caused by viral pneumonia is basically the same after treatment with HFNC and NIV,but the comfort level of HFNC is relatively higher,the incidence of complications is lower,and the psychological state of patients is better,which is conducive to shortening hospital stay and reducing hospital costs,and has higher clinical application value.

Viral pneumoniaRespiratory failureHigh flow nasal cannulaNon-invasive ventilatorComfort level

邓祯、邹小凡、范家亮、袁水生、张金红

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江西省吉安市中心人民医院呼吸与危重症学科,江西 吉安 343000

病毒性肺炎 呼吸衰竭 经鼻高流量湿化吸氧 无创通气 舒适度

吉安市科技计划

20211-025391

2024

中国伤残医学
中国康复医学会,黑龙江省截瘫研究所

中国伤残医学

影响因子:0.451
ISSN:1673-6567
年,卷(期):2024.32(13)