Clinical Observation of Deslanoside Combined with Amiodarone Hydrochloride in Emergency Treatment of Patients with Heart Failure and Rapid Atrial Fibrillation
Objective:To explore the effect of Deslanoside combined with Amiodarone Hydrochloride in emergency treatment of patients with heart failure and rapid atrial fibrillation.Methods:A total of 84 patients with heart failure and rapid atrial fibrillation admitted to Songyuan Central Hospital from January to December 2023 were selected as the study objects.They were divided into a control group and a study group according to odd and even number method,with 42 cases in each group.The control group was treated with Deslanoside,the study group was treated with Amiodarone Hydrochloride on basis of the control group.The total effective rate,occurrence of adverse reactions,cardiac function indexes,myocardial cell injury indexes and inflammatory indexes were compared between the two groups.Results:After treatment,the total effective rate of the study group was 95.24%,which was higher than 80.95%of the control group,the difference was statistically significant(P<0.05).After treatment,cardiac output,left ventricular ejection fraction and stroke output in the study group were higher than those in the control group,with statistical significance(P<0.05).After treatment,the contents of N-terminal B-type natriuretic peptide precursor,high-sensitive cardiac troponin T,creatine kinase isoenzyme and lactate dehydrogenase in the study group were lower than those in the control group,with statistical significance(P<0.05).After treatment,hypersensitive C-reactive protein and interleukin-6 in the study group were lower than those in the control group,the differences were statistically significant(P<0.05).After treatment,the incidence of adverse reactions in the study group was 7.14%,compared with 4.76%in the control group,with no statistical significance(P>0.05).Conclusion:The application of Deslanoside combined with Amiodarone Hydrochloride in emergency treatment of patients with heart failure and rapid atrial fibrillation has significant efficacy and high safety,which can effectively promote the recovery of cardiac function,alleviating myocardial cell damage and promoting the regression of inflammation.
Heart failureRapid atrial fibrillationDeslanosideAmiodarone HydrochlorideAdverse reactionsCardiac function
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维普
