Clinical Effect of Modified Decompressive Craniectomy Surgery on Patients with Severe Brain Injury
Objective:To investigate the clinical effect of modified decompressive craniectomy(DC)surgery in the treatment of severe brain injury.Methods:A total of 60 patients with severe brain injury admitted to Shandong First Rehabilitation Hospital from January 2021 to December 2023 were selected as the study objects,and were divided into a control group and a study group according to random number table method,with 30 cases in each group.The control group received conventional DC surgery treatment,and the study group received modified DC treatment.Perioperative indexes,serum inflammatory factor levels,state of consciousness,neurological function,cognitive function and the occure of complications were compared between the two groups.Results:In the study group,the time of operation,the time of return to normal intracranial pressure and the time of hospitalization were(135.85±15.63)min,(2.49±0.45)d and(18.52±1.49)d,respectively,which were shorter than(148.28±18.74)min,(3.27±0.48)d and(21.04±2.45)d in the control group,and the intraoperative blood loss was(115.22±13.59)mL,which was less than(129.57±15.12)mL in the control group,the differences were statistically significant(P<0.05).On day 7 after operation,the levels of hypersensitive C-reactive protein,interleukin-6 and tumor necrosis factor-α in the study group were(7.68±1.13)mg/L,(15.24±1.36)g/L and(10.28±1.24)μg/L,respectively,which were lower than(9.25±1.17)mg/L,(19.71±1.89)ng/L,(13.49±1.28)μg/L in the control group,the differences were statistically significant(P<0.05).One month after surgery,the scores of Glasgow Coma Score and Minimum Mental State Examination in the study group were(12.12±1.19)points and(28.65±0.57)points,respectively,which were higher than(10.63±1.08)point and(27.46±0.61)point in the control group,the score of the National Institutes of Health Stroke Scale in the study group was(8.24±1.17)points,which was lower than(9.87±1.22)points in the control group,the differences were statistically significant(P<0.05).The incidence of complications in the study group was 6.67%,which was lower than 26.67%in the control group,the difference was statistically significant(P<0.05).Conclusion:Modified DC surgery is more effective in the treatment of severe brain injury,can reduce inflammatory injury,accelerate the recovery of neurological function,consciousness and cognitive function,and fewer complications.
Severe brain injuryModified decompressive craniectomy surgerySerum inflammatory factorsCognitive function
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