摘要
目的:分析妊娠期高血压患者凝血功能指标检验结果及临床意义.方法:回顾性分析 2022年 1月—2023年 12月济宁市第三人民医院收治的100例妊娠期高血压患者及同期100例产前检查健康孕妇资料,测定凝血功能指标[凝血酶原时间(PT)、活化部分凝血活酶时间(APTT)、纤维蛋白原(FIB)、凝血酶时间(TT)]并比较,分析妊娠期高血压患者凝血功能指标检验结果及临床意义.结果:妊娠期高血压患者的FIB高于健康孕妇,PT、APTT、TT均短于健康孕妇,差异均有统计学意义(P<0.05).Logistic回归分析显示,凝血功能指标PT、APTT、TT缩短与妊娠期高血压呈负相关,FIB水平升高与妊娠期高血压呈正相关(P<0.05).绘制受试者操作特征曲线图,结果显示,凝血功能指标PT、APTT、FIB、TT诊断妊娠期高血压发生的曲线下面积分别为 0.834、0.786、0.819、0.866,均有一定的诊断价值.结论:妊娠期高血压患者凝血功能指标中PT、APTT、FIB、TT表现异常,可用于诊断妊娠期高血压,具有一定的诊断意义.
Abstract
Objective:To analyze the test results and clinical significance of coagulation function index in patients with gestational hypertension.Methods:Date of 100 patients with gestational hypertension and 100 healthy pregnant women during the same period from the Jining Third People's Hospital from January 2022 to December 2023 were retrospectively analyzed.The index of coagulation function[prothrombin time(PT),activated partial thromboplastin time(APTT),fibrinogen(FIB),thrombin time(TT)]were measured and compared,the test results and clinical significance of coagulation function index in patients with gestational hypertension were analyzed.Results:The FIB,mean systolic and diastolic blood pressure of patients with gestational hypertension were higher than those of the healthy pregnant women,and the PT,APTT and TT were shorter than those of the healthy pregnant women,the differences were statistically significant(P<0.05).The results of Logistic regression analysis showed that the redution of coagulation function indexes PT,APTT and TT were negatively correlated with gestational hypertension,while the increase of FIB level was positively correlated with gestational hypertension(P<0.05).Receiver operating characteristic curve was drawn,and the results showed that the area under the curve of coagulation function indexes PT,APTT,FIB and TT in diagnosing the occurrence of patients with gestational hypertension were 0.834,0.786,0.819 and 0.866,respectively,all of which had certain diagnostic value.Conclusion:PT,APTT,FIB and TT are abnormal in the coagulation function indexes of patients with gestational hypertension,which can be used in the diagnosis of patients with gestational hypertension and has certain diagnostic significance.
维普
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