Effect Analysis of Hemoperfusion Combined with Continuous Blood Purification in the Treatment of Patients with Severe Drug Poisoning
Objective:To explore the efficacy of hemoperfusion combined with continuous blood purification in the treatment of patients with severe drug poisoning.Methods:A total of 90 patients with severe drug poisoning admitted to Ganzhou Ganxian District People's Hospital from March 2022 to February 2024 were selected as the study objects and randomly divided into a study group and a control group,with 45 cases in each group.The control group received conventional treatment,and the study group received hemoperfusion combined with continuous blood purification treatment on the basis of the control group.The liver and kidney function,clinical indexes,rescue conditions,occurrence of complications and prognosis of the two groups were compared.Results:After treatment,serum creatinine,urea nitrogen,aspartate aminotransferase and alanine aminotransferase in two groups were lower than before treatment,and the study group was lower than the control group,the differences were statistically significant(P<0.05).The waking time,ventilator offline time and metabolic acidosis correction time of the study group were shorter than those of the control group,the differences were statistically significant(P<0.05).The incidence of complications in the study group was 4.44%,which was lower than 17.76%in the control group,the difference was statistically significant(P<0.05).After 3 months of treatment,the prognosis of the study group was better than that of the control group,the difference was statistically significant(P<0.05).The success rate of rescue in the study group was 95.56%,which was higher than 82.22%in the control group,the difference was statistically significant(P<0.05).Conclusion:Hemoperfusion combined with continuous blood purification can effectively improve the rescue success rate of patients with severe drug poisoning,reduce the risk of complications,improve the prognosis and promote the recovery of patients while improving the function of liver and kidney.
Drug poisoningHemoperfusionContinuous blood purification
国家科技期刊平台
NSTL
万方数据
