Correlation Analysis of Postoperative Pain Degree with MRI Parameters and Oxidative Stress Level in Patients with Lumbar Disc Herniation after PELD
Objective:To investigate the relationship between postoperative pain degree with MRI parameters and oxidative stress level in patients with lumbar disc herniation after percutaneous endoscopic lumbar discectomy(PELD).Methods:A total of 150 patients with lumbar disc herniation treated in Yantai Laiyang Central Hospital from March 2021 to October 2023 were selected as the study objects.All patients underwent PELD.According to the pain Visual Analogue Scale score,the patients were divided into a good recovery group(n=102)and a poor recovery group(n=48).MRI parameters(T2 values in the nucleus pulposus region and the fibrous ring region)and oxidative stress levels(reactive oxygen species,malondialdehyde and total antioxidant capacity in serum)of the two groups were compared 4 weeks after surgery,and the correlation between postoperative pain degree and MRI parameters and oxidative stress levels was analyzed by Pearson analysis.Results:Four weeks after operation,T2 values in nucleus pulposus and annulus fibrosus in good recovery group were higher than those in poor recovery group,and serum reactive oxygen species,malondialdehyde and total antioxidant capacity in poor recovery group were lower than those in good recovery group,the differences were statistically significant(P<0.05).Pearson correlation analysis showed that pain degree was negatively correlated with MRI parameters in nucleus pulposus and annulus fibrosus and serum reactive oxygen species,while pain degree was positively correlated with malondialdehyde and serum total antioxidant capacity.Conclusion:The pain degree of patients is related to the MRI parameters and the level of oxidative stress.The pain degree of patients can be predicted by MRI parameters and the level of oxidative stress.
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