Effect Analysis of Felodipine Sustained-Release Tablets Combined with Lisinopril and Hydrochlorothiazide Tablets in the Treatment of Patients with Moderate and Severe Essential Hypertension
Objective:To analyze the efficacy and safety of Felodipine Sustained-Release Tablets Combined with Lisinopril and Hydrochlorothiazide Tablets in the treatment of patients with moderate and severe essential hypertension.Methods:A total of 70 patients with moderate and severe essential hypertension treated in the Weining Yi Hui Miao Autonomous County People's Hospital From September 2022 to September 2023 were selected as the study objects and randomly divided into a study group and a control group,with 35 cases in each group.The study group was treated with Felodipine Sustained-Release Tablets combined with Lisinopril Hydrochlorothiazide Tablets,and the control group was treated with Felodipine Sustained-Release Tablets combined with Benazepril and Hydrochloride Tablets.The blood pressure level,the total effective rate and the occurrence of adverse reactions were compared between the two groups.Results:After six months of treatment,the systolic blood pressure(123.58±10.36)mmHg and diastolic blood pressure(80.14±5.07)mmHg of the study group were lower than(162.37±15.24)mmHg and(94.02±90.18)mmHg of the control group,the total effective rate 97.14%of the study group was higher than 82.86%of the control group,the incidence of adverse reactions 2.86%in the study group was lower than 14.29%in the control group,the differences were statistically significant(P<0.05).Conclusion:The Felodipine Sustained-Release Tablets Combined with Lisinopril and Hydrochlorothiazide Tablets in the treatment of patients with moderate and severe essential hypertension can achieve good therapeutic effect,obvious blood pressure reduction,and has certain safety.
Moderate and severe essential hypertensionLenopril Hydrochlorothiazide TabletsTherapeutic effectSecurity
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