Objective:To study the clinical value of serum amyloid A(SAA)in the diagnosis of multidrug resistant pulmonary tuberculosis.Methods:Thirty patients with MDR-TB infection admitted to Ganzhou Fifth People's Hospital from July 2021 to July 2022 were selected as research objects to be included in the study group,and 30 patients with other bacterial infections were selected as control group during the same period.SAA detection was performed in both groups,the detection data were recorded,and the clinical diagnostic value of SAA in MDR-TB infection was analyzed and explored.Results:The level of SAA in the study group was higher than that in the control group,the difference was statistically significant(P<0.05).Logistic regression analysis showed that SAA was associated with MDR-TB infection(OR>1,P<0.05).The ROC curve showed that the AUC of SAA in the diagnosis of MDR-TB infection was 0.838,and when the cut-offpoint was 62.430ng/mL,the best diagnostic value could be obtained.Among the 30 MDR-TB patients,11 cases had adverse treatment and 19 cases were successfully treated.The serum SAA level in the patients with adverse treatment was higher than that in the patients with successful treatment(P<0.05).Logistic regression analysis showed that SAA was associated with adverse treatment outcomes of MDR-TB infection(OR>1,P<0.05).Conclusion:SAA has high clinical diagnostic value in patients with MDR-TB infection,and can be used as a potential diagnostic marker.By detecting the level of SAA,patients with MDR-TB infection can be found earlier,which is helpful to take relevant treatment measures in time.
维普
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