Effect of Minimally Invasive Percutaneous Pedicle Screw Fixation Surgery of Patients with Thoracolumbar Fractures
Objective:To investigate effect and mechanism analysis of minimally invasive percutaneous pedicle screw fixation surgery on the prognosis of patients with thoracolumbar fractures.Methods:A total of 120 patients with thoracolumbar fracture who underwent elective surgery in the Nuclear Industry 417 Hospital from August 2019 to March 2024 were selected as the study objects,and were divided into a MIPPS group and a routine group according to the principle of random envelope lottery,with 60 cases in each group.The MIPPS group was treated with MIPPS fixation surgery,and the routine group was treated with traditional open pedicle screw internal fixation.The perioperative indexes,anterior vertebral margin height ratio,incidence of complications and serum serum glutathione peroxidase(GSH-Px)and advanced oxidation protein product(AOPP)expression were compared between the two groups.Results:The intraoperative blood loss,postoperative drainage volume and postoperative hospitalization days in the MIPPS group were lower than those in the routine group,the differences were statistically significant(P<0.05).At 3 months after surgery,the vertebral anterior margin height in the MIPPS group was higher than that in the routine group,the difference was statistically significant(P<0.05).The incidence of complications in the MIPPS group was 3.33%,Which was lower than 15.00%in the routine group,the difference was statistically significant(P<0.05).At 3 months after surgery,the serum AOPP level in the MIPPS group was lower than that in the routine group,and the serum GSH-Px level was higher than that in the routine group,the differences were statistically significant(P<0.05).Conclusion:The application of MIPPS in patients with thoracolumbar fracture can reduce the surgical trauma,reduce the incidence of complications,promote the release of serum GSH-Px,inhibit the expression of AOPP,it is beneficial to prognosis..
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