中国伤残医学2024,Vol.32Issue(19) :57-60.DOI:10.13214/j.cnki.cjotadm.2024.019.015

非肌层浸润性膀胱癌患者经尿道电切术后复发的列线图模型构建

Construction of A Nomogram Model for Recurrence in Patients with Non-Muscular Invasive Bladder Cancer after Transurethral Resection

类福炜
中国伤残医学2024,Vol.32Issue(19) :57-60.DOI:10.13214/j.cnki.cjotadm.2024.019.015

非肌层浸润性膀胱癌患者经尿道电切术后复发的列线图模型构建

Construction of A Nomogram Model for Recurrence in Patients with Non-Muscular Invasive Bladder Cancer after Transurethral Resection

类福炜1
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作者信息

  • 1. 山东省兰陵县人民医院泌尿外科,山东 临沂 276000
  • 折叠

摘要

目的:构建非肌层浸润性膀胱癌(NMIBC)患者术后复发的列线图预测模型.方法:回顾性分析 2019年 1月—2021年 4月于兰陵县人民医院泌尿外科行经尿道电切术的 112例NMIBC患者资料,随访 2年以上,根据患者术后是否复发分为复发组(n=23)及未复发组(n=89).采用多因素Logistic回归分析、Hosmer-Lemeshow(HL)、受试者工作特征(ROC)曲线、曲线下面积(AUC)、Bootstrap法构建并评价验证模型.结果:肿瘤TNM分期为T1、肿瘤分级为高分化、未接受即刻膀胱灌注、肿瘤数量为多发、糖类抗原19-9水平高是影响NMIBC患者经尿道电切术后复发的独立危险因素(P<0.05);预测模型AUC面积为 0.877(95%CI:0.803~0.952),HL检验结果显示χ2=6.628,P=0.567.结论:该列线图模型的预测效能较好,有助于临床预测NMIBC患者的复发风险.

Abstract

Objective:To establish a nomogram prediction model for postoperative recurrence of non-muscular invasive bladder cancer(NMIBC).Methods:The data of 112 patients who underwent transurethral resection of NMIBC in the Urology Department of Lanling County People's Hospital from January 2019 to April 2021 were retrospectively analyzed.The patients were followed up for more than 2 years,and were divided into a recurrence group(n=23)and a non-recurrence group(n=89)according to whether they relapsed after surgery.Multivariate Logistic regression analysis,Hosmer-Lemeshow(HL),receiver operating characteristic(ROC)curve,area under the curve(AUC)and Bootstrap method were used to construct and validate the model.Results:The TNM stage of the tumor was T1,the tumor grade was highly differentiated,the tumor did not receive immediate bladder perfusion,the number of tumors was multiple,and the level of sugar antigen 19-9 was high,which were independent risk factors for recurrence of NMIBC patients after transurethral resection(P<0.05).The AUC area of the predicted model was 0.877(95%CI:0.803~0.952),and the HL test results showed χ2=6.628,P=0.567.Conclusion:The predictive efficacy of this nomogram model is good,and it is helpful for clinical prediction of recurrence risk in patients with NMIBC.

关键词

非肌层浸润性膀胱癌/经尿道膀胱肿瘤电切术/复发

Key words

Non-Muscle invasive bladder cancer/Transurethral resection of bladder tumors/Recurrence

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出版年

2024
中国伤残医学
中国康复医学会,黑龙江省截瘫研究所

中国伤残医学

影响因子:0.451
ISSN:1673-6567
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