首页|APACHE Ⅱ和SOFA评分与血源性鲍曼不动杆菌感染患者预后的相关性研究

APACHE Ⅱ和SOFA评分与血源性鲍曼不动杆菌感染患者预后的相关性研究

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目的:探讨急性生理学与慢性健康状况评分系统Ⅱ(APACHE Ⅱ)和序贯器官衰竭(SOFA)评分与血源性鲍曼不动杆菌感染患者 28 d死亡的相关性。方法:回顾性分析 2018年 5月—2023年 5月天津医科大学总医院收治的 91例血源性鲍曼不动杆菌感染患者临床资料,通过Logistic回归分析影响血源性鲍曼不动杆菌感染患者 28 d死亡的独立危险因素。应用受试者操作特征(ROC)曲线,分析APACHE Ⅱ和SOFA评分对此类患者预后的预测价值。结果:单因素分析显示,影响血源性鲍曼不动杆菌感染患者 28 d预后的危险因素包括年龄、入住ICU、住院天数、肺炎、手术、深静脉置管、纤维支气管镜、肾功能不全、APACHE Ⅱ评分和SOFA评分等指标。多因素Logistic分析显示,APACHE Ⅱ和SOFA评分是血源性鲍曼不动杆菌感染患者 28 d预后的独立危险因素,手术是鲍曼不动杆菌感染的保护因素。ROC曲线分析结果显示,死亡组首日的APACHE Ⅱ及SOFA评分均高于存活组,差异均有统计学意义(P<0。05)。结论:血流感染当天的APACHE Ⅱ及SOFA评分对评价血源性鲍曼不动杆菌感染患者28 d预后具有重要价值。
Correlation Between APACHE Ⅱ and SOFA Scores and Prognosis of Patients with Blood-Borne Acinetobacter Baumannii Infection
Objective:To investigate the correlation between acute physiology and chronic health status score System Ⅱ(APACHEⅡ)and sequential organ failure(SOFA)score and death at 28 days in patients with blood-borne acinetobacter baumannii infection.Methods:The clinical data of 91 patients with blood-borne acinetobacter baumannii infection admitted to the General Hospital of Tianjin Medical University from May 2018 to May 2023 were retrospectively analyzed,and the independent risk factors affecting the 28-day death of patients with blood-borne acinetobacter baumannii infection were analyzed by Logistic regression.Receiver 0perating Characteristic(ROC)curve was used to analyze the prognostic value of APACHEⅡ and SOFA scores in these patients.Results:Unifactorial analysis showed that the risk factors affecting the 28-day prognosis of patients with hematogenous acinetobacter baumannii infection included age,ICU stay,length of stay,pneumonia,operation,deep vein catheterization,bronchoscopy,renal insufficiency,APACHE Ⅱ score and SOFA score.Multivariate Logistic analysis showed that APACHE Ⅱ and SOFA scores were independent risk factors for the 28-day prognosis of patients with blood-borne acinetobacter baumannii infection,and surgery was a protective factor for the infection.ROC curve analysis results showed that the APACHE Ⅱ and SOFA scores in the death group were higher than those in the survival group on the first day,with statistical significance(P<0.05).Conclusion:APACHEⅡ and SOFA scores on the day of bloodstream infection are of great value in evaluating the 28 d prognosis of patients with blood-borne acinetobacter baumannii infection.

Acinetobacter baumanniiHematogenicAcute physiology and chronic health status scoring system ⅡSequential organ failure scorePrognosis

薛晓萌、魏志勇

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天津医科大学总医院重症医学科,天津 300052

鲍曼不动杆菌 血源性 急性生理学与慢性健康状况评分系统Ⅱ 序贯器官衰竭评分 预后

2024

中国伤残医学
中国康复医学会,黑龙江省截瘫研究所

中国伤残医学

影响因子:0.451
ISSN:1673-6567
年,卷(期):2024.32(19)