血清学相关指标与2型糖尿病患者早期肾损伤的相关性分析

扫码查看

原文链接

万方数据
维普

中文摘要：目的:分析糖化血红蛋白(HbA 1c)、空腹血糖(FPG)、糖化白蛋白(GA)、尿微量白蛋白(MAU)与 2型糖尿病(T 2DM)患者早期肾损伤的相关性。方法:回顾性分析 2022年 1月—2024年 4月景德镇市第一人民医院收治的 100例T 2DM合并早期肾损伤患者资料，将其纳入研究组，选取同期收治的 97例单纯T 2DM患者资料，将其纳入对照组，另选取同期于本院体检的 98例正常体检者资料，将其纳入健康组，对比三组的HbA 1c、FPG、GA、MAU水平;用Pearson相关性分析探究HbA 1c、FPG、GA、MAU与T 2DM患者早期肾损伤的相关性。结果:研究组的HbA 1c、FPG、GA、MAU水平分别为(9。71±1。56)%、(10。88±2。26)mmol/L、(25。77±2。41)%、(36。79±5。33)mg/g，均高于对照组的(7。26±1。19)%、(8。95±1。63)mmol/L、(16。88±1。68)%、(19。72±3。46)mg/g，及健康组的(4。89±0。32)%、(4。72±0。48)mmol/L、(13。69±1。05)%、(15。33±2。59)mg/g，差异均有统计学意义(P<0。05)。Pearson相关性分析显示:HbA 1c、FPG、GA、MAU升高与T 2DM患者早期肾损伤成正相关(P<0。05)。结论:HbA 1c、FPG、GA、MAU升高与T 2DM患者早期肾损伤成正相关，各指标水平越高，患者肾损伤越严重。

外文标题：Correlation Analysis Between Serological Related Indexes and Early Renal Injury in Patients with Type 2 Diabetes Mellitus

外文摘要：Objective:To analyze the correlation between glycated hemoglobin A1c(HbA1c),fasting plasma glucose(FPG),glycosylated albumin(GA),microalbuminuria(MAU)and early renal injury in patients with type 2 diabetes mellitus(T2DM).Methods:The data of 100 T2DM patients with early renal injury admitted to the First People's Hospital of Jingdezhen from January 2022 to April 2024 were retrospectively analyzed,and were included in the study group;the data of 97 patients with simple T2DM admitted during the same period were included in the control group;the data of 98 nomal control who underwent physical examination in the hospital during the same period were included in the health group.The levels of HbA1c,FPG,GA and MAU of the three groups were compared.Pearson correlation analysis was used to explore the correlation between HbA1c,FPG,GA,MAU and early renal injury in T2DM patients.Results:The levels of HbA1c,FPG,GA and MAU in the study group were(9.71±1.56)%,(10.88±2.26)mmol/L,(25.77±2.41)%and(36.79±5.33)mg/g,respectively,which were higher than(7.26±1.19)%,(8.95±1.63)mmol/L,(16.88±1.68)%,(19.72±3.46)mg/g of the control group and(4.89±0.32)%,(4.72±0.48)mmol/L,(13.69±1.05)%,(15.33±2.59)mg/g in the healthy group,the differences were statistically significant(P＜0.05).Pearson correlation showed that The increased of HbA1c,FPG,GA and MAU were positively correlated with early renal injury in T2DM patients(P＜0.05).Conclusion:The increased of HbA1c,FPG,GA and MAU are positively correlated with early renal injury in T2DM patients,and the higher the level of each indicator,the more serious the renal injury.

外文关键词：

Type 2 diabetes mellitusRenal injuryGlycated hemoglobin A1cFasting plasma glucoseGlycated albuminMicroalbuminuria

作者：

吴昀

展开 >

作者单位：

江西省景德镇市第一人民医院内分泌科，江西景德镇 333000

关键词：

2型糖尿病肾损伤糖化血红蛋白空腹血糖糖化白蛋白尿微量白蛋白

出版年：

2024

DOI：