Effect of Xueshuantong Combined with Atorvastatin Calcium on Neurological Function and Hemorheology in Patients with Acute Cerebral Infarction
Objective:To investigate the effect of Xueshuantong combined with atorvastatin calcium(ATV)on patients with acute cerebral infarction(ACI).Methods:Clinical data of 60 ACI patients admitted to Dongguan Third Bureau Hospital from January 2020 to March 2023 were retrospectively analyzed,and were divided into a control group and a study group according to different treatment methods,with 30 cases in each group.The control group was treated with ATV,and the study group was treated with Xueshuantong combined with ATV.The neurological function,hemorheology indexes,blood lipid indexes,TCM syndrome scores and occurrence of adverse reactions were compared between the two groups.Results:After 1 month of treatment,the scores of the Modified Rankin Scale and the National Institute of Health Stroke Scale in the study group were lower than those in the control group,the differences were statistically significant(P＜0.05).After 1 month of treatment,the plasma viscosity,whole blood low tangential viscosity and whole blood high tangential viscosity of the study group were lower than those of the control group,the differences were statistically significant(P＜0.05).After 1 month of treatment,the levels of triacylglycerol,high-density lipoprotein cholesterol,total cholesterol and low-density lipoprotein cholesterol in the study group were lower than those in the control group,the differences were statistically significant(P＜0.05).After 1 month of treatment,the scores of ear brightness,hemiparalysis,mouth and eye skew,tongue strength and speech blockage in the study group were lower than those in the control group,the differences were statistically significant(P＜0.05).The incidence of adverse reactions was 20.00%in the study group,compared with 16.67%in the control group,the difference was not statistically significant(P＞0.05).Conclusion:The application of Xueshuantong combined with ATV in the treatment of ACI patients can promote the improvement of neurological deficit,adjust blood lipid index and hemorheology level,reduces symptoms such as earvision hemrparalysis and have high safety.
万方数据
维普
