Effect Analysis of Low Dose Chemolysis of Collagenase Combined with Radiofrequency Thermocoagulation in the Treatment of Patients with Lumbar Disc Herniation
Objective:To investigate the efficacy of low dose collagenase chemolysis(LDCC)combined with radiofrequency thermocoagulation(RFT)in the treatment of patients with lumbar disc herniation(LDH),and to compare the results with those of ozone ablation.Methods:The data of 102 patients with lumbar disc herniation treated in Zichuan District Hospital from January 2022 to July 2024 were retrospectively analyzed.According to different treatment methods,they were divided into a control group and a study group,with 51 cases in each group.The control group was treated with OA,the study group was treated with LDCC combined with RFT.Both groups were followed up for 4 weeks.The time index,the time when adverse symptoms disappeared and the level of lumbar dysfunction were compared between the two groups.Results:In the study group,the first time of getting out of bed after surgery,the length of hospital stay,the disappearance time of lumbago,lower limb pain,numbness and paresthesia,and muscle weakness were shorter than those in the control group,the differences were statistically significant(P＜0.05).At 1,2 and 4 weeks after treatment,the Japanese Orthopaedic Association(JOA)evaluated treatment scores in both groups were higher than before treatment;at 2 and 4 weeks after treatment,JOA scores in both groups were higher than 1 week after treatment;at 4 weeks after treatment,JOA scores in both groups were higher than 2 weeks after treatment,and the study group was higher than the control group,with statistical significance(P＜0.05).Conclusion:LDCC combined with RFT can shorten the time of getting out of bed for the first time after surgery,the time of hospitalization and the time of disappearance of adverse symptoms,and effectively alleviate lumbar dysfunction in LDH patients.
万方数据
维普
