Preparation and Antibacterial Properties of Metal Loaded Organic Framework Nanofiber Dressings
Developing wound dressings that inhibit bacterial infections to treat complex wound healing proces-ses has always been a research hotspot.The preparation of Cu MOF(HKUST-1)doped polyacrylonitrile(PAN)fi-bers for antibacterial purposes by blending electrospinning,and the improvement of the hydrophilicity of the fiber membrane by adding polyvinylpyrrolidone(PVP).MOF-PAN@PVP fibers exhibit satisfactory physical properties,such as water absorption and water vapor permeability.Due to the incorporation of HKUST-1,MOF-PAN@PVP fibers exhibit good antibacterial activity against Escherichia coli and Staphylococcus aureus.At the same time,cyto-toxicity tests have shown that MOF-PAN@PVP fibers have biocompatibility and can support cell adhesion,showing the potential to become a wound dressing.
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