(E)-4-(3,5-二溴-4-羟基苯亚甲基氨基)-2,3-二甲基-1-苯基-1,2-二氢吡唑-5-酮的合成与表征

The Synthesis and Characterization of(E)-4-(3,5-Dibromo-4-Hydroxyphenylmethylene Amino)-2,3-Dimethyl-1-Phenyl-1,2-Dihydropyrazole-5-One

黄长亮 ¹黄志浩 ¹屈莉铭 ¹于宪松¹

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作者信息

1. 山东世纪阳光科技有限公司,山东济宁 272412
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摘要

采用3,5-二溴-4-羟基苯乙醛与4-氨基安替比林以甲醇作为溶剂通过缩合反应合成了(E)-4-(3,5-二溴-4-羟基苯亚甲基氨基)-2,3-二甲基-1-苯基-1,2-二氢吡唑-5-酮.对所生成化合物采用乙醇进行结晶,5 d后获得浅黄色的晶体,其结构经X-射线单晶衍射表征,属单斜晶系,P21/c空间群,晶胞参数a=12.0197(11)Å,b=10.823 9(10)Å,c=13.392 1(12)Å,β=94.870(2)°,V=1 736.0(3)Å3,Z=4,Dx=1.780 mg·m-3,θ=2.4～25.5°,μ=4.69 mm-1,T=295(2)K,利用傅里叶变换红外光谱仪得到产物的红外光谱图.

Abstract

In this paper(E)-4-(3,5-dibromo-4-hydroxyphenylimino)-2,3-dimethyl-1-phenyl-1,2-dihydropyrazole-5-one was synthesized by condensation reaction using 3,5-dibromo-4-hydroxyphenylacetaldehyde and 4-aminoantipyrine in methanol as solvent.The generated compound was crystallized using ethanol,and after 5 days,a light yellow crystal was obtained.Its structure was characterized by X-ray single crystal diffraction,belonging to the monoclinic system,P21/c space group,cell parameters a=12.019 7(11)Å,b=10.823 9(10)Å,c=13.392 1(12)Å,β=94.870(2)°,V=1 736.0(3)Å3,Z=4,Dx=1.780 mg·m-3,θ=2.4-25.5 °,μ=4.69 mm-1,T=295(2)K.Obtain the infrared spectrum of the product using a Fourier transform infrared spectrometer.

关键词

(E)-4-(3,5-二溴-4-羟基苯亚甲基氨基)-2,3-二甲基-1-苯基-1,2-二氢吡唑-5-酮/合成/晶体结构/红外光谱

Key words

(E)-4-(3,5-dibromo-4-hydroxyphenylmethylene amino)-2,3-dimethyl-1-phenyl-1,2-dihydropyrazole-5-one/synthesis/crystal structure/infrared spectrum

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出版年

2024

山东化工

山东省化工研究院山东省化工信息中心

山东化工

影响因子：0.249

ISSN：1008-021X

参考文献量25

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