To establish an uncertain evaluation method for determination of ephedrine and pseudoephedrine in health products by HPLC-MS/MS.The uncertain sources were analyzed by constructing mathematical models of ephedrine and pseudoephedrine content.The results show that the main source of uncertainty in the determination of ephedrine and pseudoephedrine is the preparation of standard standard solution and the fitting of standard curve.When the content of ephedrine is 9.850 μg/kg,the extended uncertainty is 0.745 8 μg/kg(k=2).When the content of pseudoephedrine is 9.557 μg/kg,the extended uncertainty is 0.954 7 μg/kg(k=2).
关键词
高效液相色谱-串联质谱/保健品/麻黄碱/伪麻黄碱/不确定度
Key words
high performance liquid chromatography-tandem mass spectrometry/health care products/ephedrine/pseudoephedrine/uncertainty
维普
万方数据