摘要
本研究针对软胶囊类产品在生产过程中干燥终点难以判定和产品货架期中容易出现粘连的痛点问题,通过比对几种不同的水分测定方法,创新性地将水分活度分析检测手段应用于软胶囊胶皮表面水分的检测表征中,极大的缩短了胶皮水分的检测周期,提高检测效率,且方法稳定性良好.通过稳定性加速试验,得到水分活度指标与产品粘连之间的联系,当软胶囊胶皮水分活度低于0.30 aw时,产品在货架期内的粘连情况将得到较好的控制.本研究应用性强,可为软胶囊类产品的质量监控提供一种新的解决方案.
Abstract
Aiming at the pain points that the drying end point of softgel products in the production process is difficult to determine and adhesion phenomena is easy to occur during the product shelf period.The water activity detection method was applied to the characterization of the surface moisture of softgel rubber initiatively by comparing several different moisture measurement methods,which greatly shortened the detection cycle and improved the detection efficiency.The method has good stability.The relationship between water activity index and the phenomena of product adhesion was obtained through accelerated stability test.When the water activity of soft capsule rubber is lower than 0.30 aw,the problem of product adhesion will be better controlled in the shelf life.This study has good practicability and can provide a new solution for the quality control of softgel products.
维普
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