ICP-MS法测定鹿骨胶中铝残留量
Determination of Aluminum Residue in Deer Bone Glue by ICP-MS Method
余彩娟 1刘册家 2林超 3高习宸 4孙珊珊 4于春芳4
作者信息
- 1. 山东中医药大学药学院,山东济南 250100;山东宏济堂制药集团股份有限公司,山东济南 250103
- 2. 山东宏济堂制药集团股份有限公司,山东济南 250103;山东大学药学院,山东济南 250012
- 3. 济南市食品药品检验检测中心,山东济南 250103
- 4. 山东宏济堂制药集团股份有限公司,山东济南 250103
- 折叠
摘要
目的:建立鹿骨胶中铝残留量的测定方法.方法:采用电感耦合等离子体质谱法(ICP-MS)测定鹿骨胶中铝的残留量.结果:鹿骨胶中铝的测定值在相应的线性范围内,线性关系良好,精密度、准确度、耐用性试验中铝残留浓度相对标准偏差均小于 3.0%,平均加样回收率为99.6%(Sc内标)/103.8%(Ge内标),且相对标准偏差分别为0.6%/1.0%.结论:该方法具有良好的专属性和重现性,加样回收率符合要求,结果准确且稳定,适用于测定鹿骨胶中铝残留含量.
Abstract
Objective:To establish a method for the determination of residual aluminum in deer bone glue.Methods:The residual content of aluminum in deer bone glue was determined by inductively coupled plasma mass spectrometry(ICP-MS).Results:The determination values of aluminum in deer bone glue were in the corresponding linear range,and the linear relationship was good.The relative standard deviation of aluminum residual concentration in precision,accuracy and durability tests was less than 3.0%,the average recovery rate was 99.6%(Sc internal standard)/103.8%(Ge internal standard),and the relative standard deviation was 0.6%/1.0%,respectively.Conclusion:The method has good specificity and reproducibility,the recovery rate meets the requirements,the results are accurate and stable,and it is suitable for the determination of residual content of aluminum in deer bone glue.
关键词
鹿骨胶/铝/电感耦合等离子体质谱法Key words
deer bone glue/aluminum/inductively coupled plasma mass spectrometry引用本文复制引用
出版年
2024
NETL
NSTL
万方数据