Research Progress of Flavonoid Glycosides on Alzheimer's Disease
Alzheimer's disease is a neurodegenerative disease with a complex pathogenesis,mainly characterized by cognitive impairment and memory impairment.Flavonoids are widely present natural products in nature,and they usually combine with sugar groups to form glycosides in plants.Multiple flavonoid glycosides have been proven to improve the behavioral and cognitive abilities of Alzheimer's disease patients in clinical practice.The author analyzed the abnormal phosphorylation of Tau protein,oxidative stress,neuroinflammation β-A review of the mechanisms of action of flavonoid glycosides on Alzheimer's disease from the perspectives of five major Alzheimer's disease pathogenesis theories,including amyloid protein cascade and cholinergic damage,aims to provide reference for the research of Alzheimer's disease.
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