An Method for Determination of Cefepime Hydrochloride Intermeidiate 7-MPCA Residua Content
To establish an High-performance liquid chromatography method for the residual content determination of Cefepime Hydrochloride Intermeidiate(R,R)-7-amino-3-(1-methylpyrrolidinio)methyl-3-cephem-4-carboxylate hychloride content in reaction fluid,the reaction end point of cefepime hydrochloride synthesis process can be better controlled,and the subsequent process operation can be carried out.This established method is simple,specific,Precision,durability and good repeatability,which can be used to determine the residual content of 7-MPCA in the reaction fluid.
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