Electrochemical Coupling Reactions of Electron-deficient Imidazolium Heterocyclic Skeletons
Bisimidazolium heterocyclic skeletons have a wide range of applications in drug molecules.However,they usually need to be synthesized by oxidative coupling using toxic chemical oxidants.Recently,electrochemical synthesis methods have been developed that are more environmentally friendly.However,their application is limited to the synthesis of electron-rich structures.This work presents an electrochemical synthesis of electron-deficient bisimidazolium heterocycles that offers high yields,simple post-processing,and easy scale-up.lt has excellent potential for large-scale production and does not require an oxidizing agent,causing minimal environmental pollution.
万方数据
维普
