Preparation and Evaluation of Compound Rose Anti-anxiety Nano Microcapsule Perfume
Objective:To prepare nano-microcapsule perfume with cyclodextrin as the wall material and compound rose essential oil as the core material,and to evaluate it.Methods:The anxiolytic nanocapsules were prepared by saturated aqueous solution method,and the encapsulation efficiency of the prepared nanocapsules was measured.The hole-board test was used to evaluate the anti-anxiety effect.The duration of incense retention was evaluated by sensory evaluation and release tests.Results:The optimal preparation process of compound rose anti-anxiety nano-microcapsules was 70 ℃,the core/wall ratio was 1:5,and the homogenization speed was 12 kr/min.The inclusion rate of compound rose essential oil was 60.0％±2.8％,and the particle size of compound rose anti-anxiety nano-microcapsules was(738±5.8)nm.The results of hole plate test showed that the anti-anxiety nano-microcapsules had a relief effect on the anxiety of mice,and the fragrance retention time was longer than that of ordinary perfume.Conclusions:The anti-anxiety nano-microcapsules of compound rose prepared in this study can significantly improve the retention time and relieve anxiety,which provides a new idea for the development of long-acting perfume and new anti-anxiety nano-microcapsules perfume.
nano microcapsulesanti-anxietycompound rose essential oilperfumecyclodextrin
万方数据
维普
