Aminopyridine compounds are important organic chemical intermediates,which were widely used in pesticides,pharmaceuticals,polymers and materials.Therefore,the research on the synthesis of aminopyridine compounds is of great significance.The approach to synthesize the target compound was introduced,which was realized and manufactured from niacinamide through Hoffman degradation,amino protection,nitrification,amino deprotection and hydrogenation reactions.Its structure was confirmed by MS and 1H NMR.This synthetic route is a new method suitable for industrial production,but also the raw materials are inexpensive and readily available.
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